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首页> 外文期刊>BMJ: British medical journal >Commentary: Randomised trials of surgical and non-surgical treatment: a role model for the future
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Commentary: Randomised trials of surgical and non-surgical treatment: a role model for the future

机译：评论:手术和随机试验非手术治疗:一个角色模型未来

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摘要

Symptoms of acid reflux and heartburn are increasingly common, and doctors need to understand the benefits and risks of surgical and medical treatment from the patients' perspective when offering treatment. Obtaining reliable information from randomised controlled trials to fully inform patients is difficult, however, because of the many recognised obstacles to undertaking such trials of diverse treatments, including difficulties with recruitment and standardising treatments and the inability to provide blinding. In the linked study, Grant et al carried out a multicentre pragmatic randomised trial of minimal access surgery (laparoscopic fundoplication) compared with optimised medical management (standard proton pump inhibition) for chronic gastro-oesophageal reflux disease (GORD). The results were clear: up to 12 months after starting treatment, surgery was more effective than medical treatment at relieving symptoms related to reflux and improving general health.
机译：胃酸倒流和烧心的症状越来越普遍,医生需要了解手术的益处和风险医疗从病人的角度来看当提供治疗。信息从随机对照试验充分告知患者是困难的,然而,因为许多公认的障碍进行这些试验不同的治疗方法,包括与招聘和困难标准化治疗和无力提供致盲。基地进行了多中心务实的随机试验的最小访问手术(腹腔镜fundoplication)相比,优化医疗管理(标准质子泵抑制)慢性gastro-oesophageal反流病(GORD)。结果很明显:12个月开始治疗,手术更有效比治疗缓解症状与回流,改善整体健康。

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