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首页> 外文期刊>BMJ: British medical journal >Late onset hypogonadism Guidelines exist for diagnosis, but long term studies of treatment are needed
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Late onset hypogonadism Guidelines exist for diagnosis, but long term studies of treatment are needed

机译：晚发型存在性腺机能减退指导方针诊断,但长期治疗的研究需要

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摘要

Male hypogonadism is defined as a clinical syndrome complex, which comprises symptoms-with or without signs-and biochemical evidence of testosterone deficiency. Longitudinal population studies show that testosterone concentrations gradually decline with age. One recent study reported the prevalence of hypogonadism to be 4.2% between 30 and 50 years and 8.4% between 50 and 79 years, although other studies have indicated that it may be higher.The terminology to explain the development of hypogonadism with ageing is controversial. Terms such as male menopause and andropause imply that all men develop this condition, which is not the case. The term late onset hypogonadism has been proposed as a clearer clinical description and is now the preferred terminology of several major international societies. Late onset hypogonadism is defined as "a clinical and biochemical syndrome associated with advancing age and characterised by typical symptoms and a deficiency in serum testosterone levels. It may significantly reduce quality of life and adversely affects the function of multiple organ systems." A diagnosis of late onset hypogonadism can be made only after excluding other causes of hypo-gonadism by appropriate investigation.
机译：男性性腺机能减退的定义是一个临床症状复杂,包括症状的或没有迹象和生化的证据睾丸激素缺乏症。研究表明,睾酮浓度随着年龄的增长逐渐下降。报道的患病率性腺机能减退4.2%的30至50年和8.4%的50之间79年,尽管其他的研究表明它可能更高。解释性腺机能减退的发展老龄化是有争议的。更年期和男人更年期暗示所有的男人开发这个条件,这并非如此。这个词晚发型性腺机能减退提出作为临床描述和清晰现在几个主要的首选术语国际社会。被定义为“一个临床和生化综合症与年龄有关典型的症状和特征缺乏血清睾酮水平。大大降低生活质量和不利影响多个器官的功能系统。”之后才可以排除其他原因的hypo-gonadism通过适当的调查。

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