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Efficacy of antidepressants in adults

机译:成人抗抑郁药物的效果

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The National Institute for Health and Clinical Excellence (NICE) recently recommended that anti-depressants, in particular selective serotonin reuptake inhibitors, should be first line treatment for moderate or severe depression.1 This conclusion has broadly been accepted as valid.2 The message is essentially the same as that of the Defeat Depression Campaign in the early 1990s, which probably contributed to the 253% rise in antidepressant prescribing in 10 years.1 From our involvement in commenting on the evidence base for the guideline we believe these recommendations ignore NICE data. The continuing concern that selective serotonin reuptake inhibitors may increase the risk of suicidal behaviour. means there needs to be further consideration of evidence for the efficacy of antidepressants in adults as there has been in children.
机译:国家健康和临床研究所卓越(NICE)最近建议抗抑郁药,特别是选择性5 -羟色胺再摄取抑制剂,应该放在第一位行治疗中度或重度depression.1接受valid.2一样战胜萧条运动在1990年代早期,可能导致了抗抑郁药将增长253%在10 years.1处方评论指南的证据基础我们相信这些建议忽略好了数据。5 -羟色胺再摄取抑制剂可能会增加自杀行为的风险。进一步考虑的证据抗抑郁药在成年人的效果一直在孩子。

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