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首页> 外文期刊>Journal of the peripheral nervous system: JPNS >Relationship between physical performance and quality of life in Charcot-Marie-Tooth disease: a pilot study
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Relationship between physical performance and quality of life in Charcot-Marie-Tooth disease: a pilot study

机译：物理性能之间的关系疾病:腓骨肌萎缩的生活质量试点研究

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摘要

Charcot-Marie-Tooth (CMT) is a rare inherited peripheral neuropathy in which quality of life (QoL) is reduced compared with the general population. This paper investigates the relationship between QoL and physical performance in people with CMT with the aim of identifying avenues for future research into rehabilitation strategies. Cross-sectional data was obtained from 10 participants (5 men, 5 women, age 46 +/- 13 years, height 1.7 +/- 0.1 m, body mass 77 +/- 17 kg) with CMT (CMT1A n=5; CMT-X n=3; unknown genetic origin n=2). Participants were evaluated for QoL, falls efficacy (FES), balance, mobility, muscle strength, and power. Physical component score (PCS) of the Short Form-36 (SF-36) was significantly and directly related to higher leg press power (r=0.75, p=0.02). Better FES scores were significantly related to faster habitual gait speed (r=-0.70, p=0.02), left hip abduction, and seated row strength (r=-0.68, p=0.03; r=-0.73, p=0.03, respectively). Future research should aim to substantiate these preliminary findings in a larger cohort and investigate whether interventions targeting muscle strength and power can improve QoL and mobility outcomes in people with CMT.
机译：(CMT)腓骨肌萎缩是一种罕见的遗传周围神经病变的生活质量(QoL)减少而一般人口。生命质量和物理性能之间的关系在人与CMT识别的目的未来研究的方向为康复策略。来自10个参与者(5人,5名妇女,年龄46 + / -13年,身高1.7 + / - 0.1米、体重77 + / -17公斤)与CMT (CMT1A n = 5;遗传起源n = 2)。生命质量、功效(菲斯),平衡,流动性,肌肉力量和权力。评分(pc)的短Form-36 (SF-36)明显和直接关系到更高的腿媒体力量(r = 0.75, p = 0.02)。有显著联系更快的习惯吗步态速度(r = -0.70, p = 0.02),左臀部绑架,和坐行力量(r = -0.68, p = 0.03;分别为r = -0.73, p = 0.03)。应该这些初步证实结果在一个更大的群体和调查是否针对肌肉力量的干预措施和功率可以提高生命质量和流动性的结果在CMT。

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