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Validation of a New Arabic Version of the Neuropathic Pain Diagnostic Questionnaire (DN4)

机译:验证新的阿拉伯语版本的神经性疼痛的诊断调查问卷(DN4)

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The Douleur Neuropathique 4 (DN4) questionnaire was developed for screening neuropathic pain. The purpose of this work was to validate the DN4 questionnaire in the standard Arabic language. First, the questionnaire was translated and semantically adapted to Arabic according to the international guidelines for cross-cultural adaptation. Second, a prospective observational study was performed to validate this questionnaire. A total of 195 patients with chronic pain (n = 99 with neuropathic pain and n = 96 without neuropathic pain) were enrolled in the study. The internal consistency Kuder-Richardson's Formula 20 for the whole DN4 questionnaire was 0.86 (P < 0.001) and the intraclass correlation coefficient 0.99 (95% CI: 0.99 to 1.00). The test-retest reliability kappa coefficient for each item ranged from 0.92 to 1.00. Using a receiver-operating characteristic (ROC) curve analysis, the areas under the curve were 0.94 and 0.97 for the 7-item DN4 and 10-item DN4, respectively. A cut-off score of 3 resulted in a sensitivity of 97.0% and a specificity of 82.3% for the 7-item DN4, while a cut-off score of 5 for the 10-item DN4 resulted in a sensitivity of 93.0% and a specificity of 95.8%. Tingling, numbness, and hypoesthesia to touch and to pricking were the most discriminating pain items. The sensitivity and specificity of the 7-item DN4 and 10-item DN4 were not influenced by either pain severity or educational level. In conclusion, this new Arabic version DN4 questionnaire is a simple, reliable, and valid tool for discriminating between neuropathic and non-neuropathic pain. It represents a useful tool in clinical setting and population-based studies.
机译:的Douleur Neuropathique 4 (DN4)问卷开发筛选神经性疼痛。这项工作的目的是验证DN4问卷调查在标准阿拉伯语。首先,问卷被翻译语义上适应显示阿拉伯语国际跨文化指南适应。研究进行了验证问卷调查。慢性疼痛与神经性疼痛和n (n = 99= 96没有神经性疼痛)参加这项研究。20对整个DN4 Kuder-Richardson的公式问卷为0.86 (P < 0.001)组内相关系数0.99(95%置信区间CI:0.99到1.00)。每项系数从0.92不等1.00. (中华民国)曲线分析,曲线下的面积分别为0.94和0.97的7-item DN4和问题分别DN4。的敏感性为97.0%,特异性82.3% 7-item DN4,而截止得分5 DN4导致的问题敏感性为93.0%,特异性为95.8%。触摸和刺痛、麻木、感觉迟钝刺痛是最歧视的痛苦物品。7-item DN4 DN4和问题没有影响疼痛严重程度或教育水平。结论,这个新的DN4阿拉伯语版本问卷调查是一种简单、可靠和有效的区分神经性和的工具non-neuropathic疼痛。在临床设置和以人群为基础的研究。

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