Antiphospholipid Antibodies and the Antiphospholipid Syndrome: From Coagulation to the Clinic

Rita Selby; Jameel Abdulrehman

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Antiphospholipid Antibodies and the Antiphospholipid Syndrome: From Coagulation to the Clinic

机译：Antiphospholipid抗体和Antiphospholipid综合症:从凝固诊所

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Antiphospholipid syndrome (APS) is a systemic, autoimmune disorder characterized by the presence of antiphospholipid antibodies (APLA) directed to various plasma proteins bound to anionic phospholipids. The clinical syndrome of APS is variable, resulting commonly in venous or arterial thrombosis and/or pregnancy morbidity and is defined by clinical and laboratory consensus criteria (1). "Noncriteria" clinical presentations and severe presentations such as catastrophic APS (a syndrome of multiorgan failure) are less common. Both criteria and noncriteria presentations are described in Table 1.

机译：Antiphospholipid综合征(APS)是一个系统,自身免疫性疾病的存在antiphospholipid抗体(APLA)指向各种血浆蛋白绑定到阴离子磷脂。变量,导致静脉或一般动脉血栓形成和/或妊娠发病率并被定义为临床和实验室(1)共识标准。演讲和严重的报告等灾难性的APS (multiorgan综合症失败)不太常见。noncriteria演讲中描述表1.

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《The journal of applied laboratory medicine.》 |2022年第1期|373-378|共6页
作者
Rita Selby; Jameel Abdulrehman;
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作者单位

Department of Laboratory Medicine & Pathobiology & Department of Medicine, University of Toronto;

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原文格式 PDF
正文语种英语
中图分类诊断学;
关键词
Antiphospholipid Syndrome; Antiphospholipid Antibodies; clinicPlasma ProteinsMultiple Organ FailureAutoimmune Disease;

机译：抗体;clinicPlasma ProteinsMultiple器官;

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1. Study of the Effect of Intralipid Infusion during Pregnancy as an Additive Treatment for Reducing Pregnancy Complications Caused by Antiphospholipid Antibody Syndrome [J] . Adel E. El-Gegawy, Hashem A. Lotfy, Shereef L. Elshwaikh 妇产科期刊（英文） . 2021,第004期
2. Response to letter to the editor: catastrophic antiphospholipid antibody syndrome and multiple organ dysfunctions in critically ill patients with COVID-19 Multiple organ dysfunction syndrome in SARS-CoV-2 infection: are antiphospholipid antibodies the killer? [J] . Robba Chiara, Battaglini Denise, Pelosi PaoloRocco Patricia R. M. Expert review of respiratory medicine . 2020,第12期

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3. The IgM isotype of anti-annexin A5 antibodies and multiple positivity of conventional antiphospholipid antibodies: increasing the number of clinical manifestations of primary antiphospholipid syndrome [J] . Becarevic Mirjana, Stojanovic Ljudmila, Ignjatovic SvetlanaDopsaj Violeta Clinical rheumatology . 2016,第5期

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4. Antiphospholipid antibody and antiphospholipid antibody syndrome [J] . Susumu current opinion in rheumatology . 1992,第5期

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5. An application of an explicit water model to a glycoprotein -antibody complex [C] . Kaori Ueno-Noto 日本化学会春季年会講演予稿集 . 2018

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6. Qing Re Liang Xue Decoction Alleviates Hypercoagulability in Kawasaki Disease [O] . Jiao-yang Chen, Ji-ming Yin, Zhong-dong Du, 2015

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8. Cavitands, Liquid Crystals and Antibodies: Materials for Integrated Chem/Bio. Sensing [R] . Shenoy, D. K. , Feresenbet, E. , Anderson, G. , 2004

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Antiphospholipid Antibodies and the Antiphospholipid Syndrome: From Coagulation to the Clinic

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