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首页> 外文期刊>Human psychopharmacology: clinical and experimental >Combination of ziprasidone and clozapine in treatment-resistant schizophrenia.
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Combination of ziprasidone and clozapine in treatment-resistant schizophrenia.

机译：齐拉西酮和氯氮平的组合难治性精神分裂症。

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摘要

In cases of treatment-resistant schizophrenia the combined application of antipsychotic drugs often becomes necessary. Clozapine has been combined successfully with other atypical antipsychotic drugs such as risperidone or amisulpride in the past.We report the difficult treatment of a 28-year-old schizophrenic woman. Psychotic symptoms were found resistant to monotherapy with clozapine or ziprasidone. In contrast, combined application led to a marked improvement in both positive and negative symptoms of schizophrenia along with a decrease of side effects.The reported combination is a promising option in cases of treatment-resistant schizophrenia and should be further evaluated in prospective studies.
机译：在例难治性精神分裂症经常联合应用抗精神病药物成为必要。成功地与其他非典型抗精神病药物醇和四种药物如利培酮或过去。28岁的精神分裂症的女人。症状被发现对单一疗法氯氮平或齐拉西酮。应用程序导致了显著的改善积极的和消极的精神分裂症的症状随着减少副作用。报告是一种很有前途的选择组合例难治性精神分裂症和应该进一步评估在未来研究。

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