• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Human psychopharmacology: clinical and experimental >Drug utilization review of risperidone for outpatients in a tertiary referral hospital in Singapore.
【24h】

Drug utilization review of risperidone for outpatients in a tertiary referral hospital in Singapore.

机译：利培酮的药物利用评估在三级转诊医院的门诊病人新加坡。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

BACKGROUND: Risperidone has been used in Singapore for schizophrenia since 1996. However, little information is available on its utilization pattern. OBJECTIVE: To examine the risperidone utilization pattern in the Psychiatric Outpatient Clinic of the National University Hospital. METHOD: Medical records of all outpatients with schizophrenia prescribed with risperidone from 1 September1999 to 31 August 2000 were reviewed. RESULTS: A total of 417 risperidone prescriptions were dispensed for 130 outpatients (50 male, 80 female) during the study period. The mean +/- SD daily doses for prescriptions and for patients were 2.3 +/- 1.3 mg and 2.1 +/- 1.1 mg, respectively. Among these patients, 28 (21.5%) received at least one concomitant conventional antipsychotic and 71 (54.6%) received a concomitant anti-Parkinsonian agent. Logistic regression analysis suggested that a higher risperidone dose was associated with the greater probability of anti-Parkinsonian agent usage. CONCLUSIONS: The mean risperidone doseduring the study period was towards the lower end of recommendation for schizophrenia. Further study is warranted to confirm and explain the pattern of low-dose risperidone, and the high use of concomitant conventional antipsychotics and anti-Parkinsonian agents in Singapore. Elucidation of these would provide a valuable insight for the management of Asian patients with schizophrenia using risperidone. However, the current data indicate that the practice of using a lower dose of risperidone could represent better affordability and an improved cost-effectiveness ratio of risperidone compared with conventional antipsychotics in Asian patients.
机译：背景:利培酮在新加坡已经使用自1996年以来为精神分裂症。信息的利用率模式。在精神科门诊利用模式国立大学医院的诊所。方法:所有门诊病人的医疗记录精神分裂症与利培酮从1规定综述了2000年8月31日的选择。结果:总共有417利培酮处方分发了130门诊(50男,80女)在研究期间。每日剂量处方和病人是2.3 + / - 1.3毫克和2.1 + / - 1.1毫克,分别。收到至少一个伴随的传统抗精神病药物和71年(54.6%)接受了伴随anti-Parkinsonian代理。回归分析表明,更高利培酮剂量就越大概率anti-Parkinsonian代理使用。结论:利培酮doseduring均值研究期间的低端建议为精神分裂症。才能保证证实和解释的模式吗使用小剂量利培酮,高伴随传统抗精神病药物和在新加坡anti-Parkinsonian代理。这些将提供一个有价值的说明了解亚洲患者的管理精神分裂症使用利培酮。当前数据表明使用的做法低剂量的利培酮可以代表更好的承受能力和改进利培酮相比的成本效益比与传统抗精神病药物在亚洲病人。

著录项

相似文献

  • 外文文献
  • 中文文献
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号