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Enhanced cognitive performance and cheerful mood by standardized extracts of Piper methysticum (Kava-kava).

机译:增强认知能力和愉快的心情Piper methysticum的标准化提取物(Kava-kava)。

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摘要

The acute effects of the herbal anxiolytic Kava-kava (Piper methysticum G. Forster) on emotional reactivity and cognitive performance were investigated in a double-blind randomized placebo-controlled trial involving healthy volunteers. Subjects' reports of mood change were assessed with the state-trait-cheerfulness-inventory, which measures the three concepts of cheerfulness, seriousness and bad mood as both traits and states. Cognitive performance was examined with the Sperling partial report and the Sternberg item recognition task, which were used as an index for visual attention and short-term memory processing. The intake of a single dose of Kava extract (300 mg; p.o.) led to an increase in state cheerfulness, while the phytopharmacon did not influence state seriousness and bad mood. The mood-elevating effects of Kava were most prominent in trait cheerful subjects, indicating that trait cheerfulness moderated the drug-induced increase in cheerful mood. Furthermore, Kava improved the accuracy and the speed of performing the partial report and the item recognition task, indicative of a beneficial effect of the phytopharmacon on visual attention and short-term memory retrieval, respectively. Thus, unlike conventional benzodiazepine-type anxiolytics, which tend to impair cognitive performance and to increase the occurrence of negative affective states, Kava is a potent anxiolytic agent, which, additionally, can facilitate cognitive functioning and can increase positive affectivity related to exhilaration.
机译:的急性影响中药抗焦虑药卡瓦胡椒(Piper methysticum福斯特)情感反应和认知能力研究了在一个双盲随机安慰剂对照试验涉及健康志愿者。评估与state-trait-cheerfulness-inventory,快乐的三个概念,措施和坏情绪特征和严重性州。斯珀林部分报告,斯特恩伯格项目识别任务,作为指数视觉注意力和短期记忆处理。提取(300毫克;快乐,而phytopharmacon不影响国家严肃和坏心情。卡瓦胡椒最情绪提升的影响突出特征的主题,表明特征快乐主持药物引起的增加愉悦心情。此外,卡瓦胡椒的准确性和提高速度和执行部分报告项目识别任务,表明一个有益的phytopharmacon在视觉注意力的效果分别和短期记忆检索。因此,与传统的benzodiazepine-type抗焦虑药,这往往会影响认知性能和增加的发生消极情感状态、卡瓦胡椒是有效的抗焦虑剂,此外,可以促进认知功能和可以增加积极的情感作用与兴奋。

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