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首页> 外文期刊>Human psychopharmacology: clinical and experimental >The effect of a herbal medicine (Mao-to) for the prevention of interferon-induced psychiatric complications in chronic hepatitis C: a pilot study.
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The effect of a herbal medicine (Mao-to) for the prevention of interferon-induced psychiatric complications in chronic hepatitis C: a pilot study.

机译：预防干扰素诱导的精神在慢性丙型肝炎并发症:一名飞行员研究。

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OBJECTIVE: To evaluate the efficacy of a herbal medicine (Mao-to) on psychiatric complications caused by IFN, and to examine the relationship between depression and microcirculation. METHODS: Twelve patients with chronic hepatitis C and a past history of IFN-induced depression were enrolled in this study. Their mental state was evaluated by the self-rating depression scale (SDS)>==40, or M-R of the Cornell medical index (CMI)>==10. Each patient received a daily dose of 6 million units of IFN-beta for 8 weeks, and Mao-to was given orally four times a day during the IFN-beta course. RESULTS: All patients in this study completed a full course of IFN. Mean CMI scores (M-R) had significantly decreased at the end of the treatment. Mean erythrocyte aggregability and erythrocyte deformability had also significantly decreased at the end of treatment. CONCLUSION: Mao-to might be useful for preventing the incidence of depression in patients with chronic hepatitis C being treated with IFN. The mechanism by which Mao-to prevents depression is suggested to be through the improvement of microcirculation.
机译：目的:评估草药的疗效干扰素引起的,检查的关系在抑郁和微循环。十二个慢性丙型肝炎患者和一个过去的历史IFN-induced抑郁参加本研究。自我评估抑郁量表评估(SDS) > = = 40岁或先生的康奈尔医学指数(CMI) > = = 10。600万单位IFN-beta 8周,IFN-beta课程。本研究完成了一个完整的干扰素。CMI分数(先生)明显下降结束治疗。aggregability和红细胞可变形性年底也显著降低治疗。防止抑郁的发病率慢性丙型肝炎患者接受治疗干扰素。抑郁症是建议通过改善微循环。

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