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The efficiency of a carbamazepine-mianserin combination scheme in opiate detoxification.

机译:carbamazepine-mianserin的效率组合方案在鸦片解毒。

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A recent comparative randomized double-blind study has suggested the utility of a carbamazepine/mianserin combination as a treatment for opiate withdrawal. The aim of the present study was to explore the feasibility and efficiency of this combination under naturalistic conditions. Five hundred and fifty mostly polysubstance abusing patients treated with a standardized scheme combining carbamazepine and mianserin were assessed with regard to deviations to the protocol, used comedications and retention in treatment.Three hundred and sixty three patients (66.0%) received the carbamazepine/mianserin combination as specified by the standardized protocol. In 350 patients (63.7%) the whole 10 days was completed. The most frequently used p.r.n. medications were for anxiety (47.5%) and insomnia (54.5%).The treatment of opiate withdrawal with a carbamazepine/mianserin combination scheme in an inpatient setting seems to be feasible and applicable with few adaptations to most patients, and may represent an interesting treatment option for multidrug users. Copyright 2004 John Wiley & Sons, Ltd.
机译:最近比较随机双盲研究建议的效用卡马西平/米安色林作为一个组合治疗鸦片撤军。本研究旨在探讨和可行性这个组合在自然的效率条件。患者多重药物滥用结合卡马西平和标准化方案米安色林评估偏差使用的协议,comedications和保留在治疗。病人(66.0%)接受了卡马西平/米安色林组合指定通过标准化的协议。整个10天完成(63.7%)。常用的是p.r.n.药物焦虑(47.5%)和失眠(54.5%),治疗的鸦片撤军卡马西平在一个/米安色林组合方案住院设置似乎是可行的适用一些适应大多数患者,可能代表了一个有趣的治疗选择多用户。儿子,有限公司

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