• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Human psychopharmacology: clinical and experimental >Factors associated with complex visual hallucinations during antidepressant treatment.
【24h】

Factors associated with complex visual hallucinations during antidepressant treatment.

机译：与复杂的视觉相关的因素抗抑郁药物治疗期间的幻觉。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Published case reports on complex visual hallucinations (CVH) occurring during antidepressant (AD) treatment were reviewed. Thirteen cases of CVH associated with SSRI treatment, 16 cases during tricyclic drug treatment and seven cases with other AD drug treatments were found. Nine patients were taking concomitant drugs while on therapy with SSRIs and four had a neurological disease in addition to depression. The cholinergic impoverishment occurring in dementia states or during concomitant therapy with anticholinergic drugs could increase the sensitivity to serotonergic agonists, triggering the manifestation of CVH. During tricyclic drug treatment, half of the reports were of hypnopompic or hypnagogic hallucinations and this can be associated with the effects of tricyclics (TCA) on sleep architecture. It is likely that the potent anticholinergic effect of amitriptyline was potentiated in a situation of a rapidly changing state of consciousness. In general, the review supports the view that an imbalance between serotonin and acetylcholine systems is at the root of AD-induced CVH, with a profile defined by a cholinergic hypoactivity and a serotonergic hyperactivity. Caution is needed when administering a combination of serotonergic and anticholinergic AD in the treatment of the demented population and in other already compromised patients because there is a risk of precipitating CVH.
机译：病例报告发表在复杂的视觉幻觉(CVH)时发生综述了抗抑郁药(广告)治疗。13例CVH与SSRI有关在三环类药物治疗,16例与其他广告药物治疗,7例治疗方法被发现。相伴与ssri类药物在治疗除了四个有一个的神经疾病抑郁症。发生在或在痴呆状态同时用抗胆碱能药物治疗可以增加对血清素激活的吗受体激动剂,引发CVH的表现。在三环类药物治疗,一半的报告是半醒的或催眠的幻觉,这可以联系在一起三环抗抑郁药(TCA)对睡眠的影响体系结构。抗胆碱能作用,阿米替林强在一个迅速变化的情况的意识状态。支持的观点之间的不平衡5 -羟色胺和乙酰胆碱系统的根AD-induced CVH,概要文件定义的胆碱能活动减退和血清素激活的多动。管理结合血清素激活的和抗胆碱能AD的治疗精神错乱的人口和其他了受损的患者因为有风险沉淀CVH。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号