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An Unusual Case of Metastatic Seminoma in a Dog

机译:一个不寻常的情况下转移性精原细胞瘤的狗

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An 8 yr old, reportedly castrated male Boston terrier presented with a history of generalized hyperesthesia and intermittent shifting leg lameness. Physical examination revealed a caudal abdominal mass and bilateral shoulder pain. A complete blood count, serum biochemistry panel, and urinalysis were unremarkable. Thoracic radiographs demonstrated bony proliferation and lysis of the third sternebra, an expansile lesion of the left tenth rib, and lucency in both proximal humeral metaphyses. Abdominal radiographs and ultrasound revealed a soft tissue mass within the caudoventral right abdomen. Ultrasonography also revealed an enlarged lymph node within the right retroperitoneal space. Exploratory laparotomy identified the mass as a retained testicle. A cryptorchidectomy, lymph node biopsy, and bilateral percutaneous core biopsies of the proximal humeri were performed. Histopathologic examination revealed malignant seminoma of the testicle with metastasis to lymph node and bone. Adjuvant chemotherapy was recommended, but it was declined by the owner. All follow-up was lost. This case highlights a unique case for causative hyperesthesia secondary to a novel site of metastasis from malignant seminoma. Metastasis to bone has not been reported in humans or dogs and represents a very unusual and aberrant variant of the normally relatively benign biological behavior of seminoma in the dog.
机译:一个8岁,据说被阉割的雄性波士顿梗了广义的历史感觉过敏和间歇移动的腿残废。腹部肿块和双边肩痛。完整的血细胞计数,血清生化面板,和尿液是不起眼的。射线照片证明骨和增殖第三sternebra消散,膨胀性的病变左十肋骨,和光亮肱骨近端metaphyses。片和超声波显示软组织质量在caudoventral右腹部。超声也发现淋巴结肿大在右腹膜后空间节点。开腹探查术质量作为标识保留睾丸。淋巴结活检,双边经皮核心活检的肱骨近端。病理检查发现恶性睾丸精原细胞瘤的淋巴转移节点和骨头。推荐,但减少了所有者。所有后续了。独特的诱发感觉过敏二级一个小说网站转移的恶性精原细胞瘤。在人类和狗,代表一个非常不同寻常的正常的和异常的变体相对良性的精原细胞瘤的生物学行为的狗。

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