...
首页> 外文期刊>Journal of basic and clinical physiology and pharmacology. >Silver nanoparticles influenced rat serum metabolites and tissue morphology
【24h】

Silver nanoparticles influenced rat serum metabolites and tissue morphology

机译:银纳米粒子的影响大鼠血清代谢产物和组织形态

获取原文
获取原文并翻译 | 示例
           

摘要

Background: Silver nanoparticles (AgNPs) are increasingly and extensively being applied for biomedical purposes. However, studies on the safety/toxicity profiles of AgNPs are limited. This necessitates the further studies in this direction. Here, we studied the effect of AgNP administration on rat serum metabolites and tissue morphology.Methods: Rats were randomly distributed into eight groups of five animals each. Oral administration of AgNPs to rats at 100,1000, and 5000 mg/kg was done daily and carried out for 7, 14, and 21 days alternately. The control received distilled water. Animals were sacrificed under diethyl ether anesthesia 24 h after cessation of last treatments. The blood and vital organs were harvested and prepared for biochemical and histopathology examinations, respectively.
机译:背景:银纳米颗粒(AgNPs)越来越广泛的被应用生物医学的目的。安全/ AgNPs毒性资料是有限的。这需要进一步的研究方向。在大鼠血清代谢物和管理组织形态。分成八个五组动物每一个。100、1000和5000毫克/公斤是每日完成的进行了7、14和21天交替。控制收到了蒸馏水。牺牲在乙醚麻醉24h后停止治疗。和重要器官是收获和准备生化和组织病理学检查,分别。

著录项

相似文献

  • 外文文献
  • 中文文献
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号