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首页> 外文期刊>MIMS Doctor. >Cilostazol + aspirin/clopidogrel may reduce recurrent ischaemic stroke risk
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Cilostazol + aspirin/clopidogrel may reduce recurrent ischaemic stroke risk

机译：西洛地唑氯吡格雷+阿司匹林可能会减少复发性缺血性中风的风险

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摘要

The addition of the phosphodi-esterase 3 inhibitor cilostazol to either aspirin or clopidogrel reduced the risk of recurrent stroke among patients at high risk of recurrence following a non-cardioembolic ischaemic stroke, according to the CSPS.com* study conducted in Japan. Eight to 180 days following the onset of a non-cardioembolic ischaemic stroke, 1,879 patients aged 20-85 years at high risk for stroke recurrence** who were on aspirin (81-100 mg) or clopidogrel (50-75 mg) treatment were randomized to continue receiving aspirin or clopidogrel alone (monotherapy; n=947, mean age 69.7 years, 27.9 percent female), or cilostazol (100 mg BID) plus either aspirin or clopidogrel (dual therapy; n=932, mean age 69.6 years, 31.7 percent female).
机译：添加phosphodi-esterase 3抑制剂西洛地唑阿司匹林或氯吡格雷减少中风复发的风险后复发的高危患者non-cardioembolic缺血性中风,据CSPS.com *在日本进行的研究。启动后的180天non-cardioembolic缺血性中风,187920 - 85岁的病人在中风的风险很高递归* *人在阿司匹林(81 - 100 mg)或氯吡格雷(50 - 75毫克)治疗被随机分配继续接受阿司匹林或氯吡格雷单(单药治疗;27.9%的女性),或西洛地唑(100毫克)+阿司匹林或氯吡格雷(双重疗法;n = 932,平均年龄69.6岁,31.7%的女性)。

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