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The value of ADC values with different b values in Gleason classification of prostate cancer

机译:格里森前列腺癌分型中不同b值的ADC值

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Purpose To assess the performance of ADC values in stratifying high- and low-risk groups of Gleason score of prostate cancer. Materials and methods 370 cases of prostate cancer who met the selection criteria between October 2015 and May 2019 were collected in the study. MRI sequences included high-resolution transverse T2WI and DWI (b = 0, 1000, 2000 and 3000 s/ mm2). Surgical pathological results were obtained in all cases. The ADC values of prostate cancer lesions were measured by two radiologists and the consistency and reproducibility analysis were done. The ADC values were compared between high-risk group and low-risk group lesions and the receiver operating characteristic (ROC) curve was used to evaluate the value of ADC values of different b values in distinguishing high-risk group from low-risk group of Gleason of prostate cancer. Results The consistency and reproducibility of ADC values measured by two radiologists in high- and low-risk group of Gleason of prostate cancer were excellent. The ADC values for high-risk group of Gleason of prostate cancer were significantly lower than those for low-risk group (j? < 0.05). The area under the ROC curve (AUC) of different b values distinguishing high-risk group from low-risk group of Gleason of prostate cancer were 0.651, 0.656, 0.692 (reader1) and 0.658, 0.653, 0.695 (reader2), respectively. The diagnostic efficacy of b value (3000 s/mm2) is the highest. Conclusions The b value of 3000 s/mm2 is the most useful in differentiating high-risk group from low-risk group of Gleason of prostate cancer.
机译:目的评估性能的ADC值分层高和低风险组格里森分数的前列腺癌。370例前列腺癌会见了谁选择标准在2015年10月和5月之间2019年收集的研究。包括高分辨率横向T2WI和醉酒驾车(b = 0、1000、2000和3000年代/平方毫米)。在所有情况下病理结果。前列腺癌的病灶的ADC值通过测量两个放射科医生和一致性和再现性分析。高危组和之间的值进行比较低风险组病变和接收操作特征(ROC)曲线是用来评估ADC值的值不同的b值区分高危组和低风险群格里森的前列腺癌。ADC值的一致性和再现性通过测量两个放射科医生在高收入和低风险组的格里森前列腺癌太好了。格里森的前列腺癌明显低于低风险组(j ?ROC曲线下的面积(AUC)不同的b值区分高危人群低风险组的格里森前列腺癌0.651、0.656、0.692 (reader1), 0.658, 0.653,分别为0.695 (reader2)。功效(3000 s /平方毫米)的b值是最高的。结论b值3000 s /平方毫米用于区分高危人群低风险组的格里森前列腺癌。

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