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首页> 外文期刊>Scientia Africana: An International Journal of Pure & Applied Sciences >EVALUATION OF EUPHORBIA POISSONII PAX FOR THE FORMULATION OF AN
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EVALUATION OF EUPHORBIA POISSONII PAX FOR THE FORMULATION OF AN

机译：大戟PAX用于配制

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摘要

This research was designed to explore the biological effects of compounds isolated from Euphorbia poissoni pax for the formulation of an Incapacitating Agent against Albino rat; which will serve as an indigenous weapon for the Nigerian defence systemand also as an insecticide. Chloroform extracts of Euphorbia poissoni pax was subjected to preliminary phytochemical screening to ascertain the presence of phenolic compounds, alkaloids, saponins, and terpenoids. Fourier-Transform Infrared (FT-IR) spectroscopy and Gas Chromatography-Mass Spectrometry (GC-MS) analysis indicated the presences of some chemical compounds including (4-(4-Hydroxyphenyl)-4-methyl-2-pentanone) trimethylsilyl Ether, n-Hexadecanoic acid, Carbonic acid(lR)-(-)-menthyl nonyl ester,13-Octadecenoic acid methyl ester, 1,3,5-triazine, 2-chloro-4,6-bis(mthylthio) and Phthalic acid, 6-ethyloct-3-yl-2-ethylhexyl ester. In the chloroform extract. The LD50 of the plant extract was calculated to be 1733.33 mg/kg, which is within the OECD (Organization of Economic Cooperation and Development) guidelines. The extract exerted a potent biological activity at 1000 mg/kg on applying under pressure on the rat skin and incapacitated the rat for 2 minutes. The extract showed an effective insecticidal effect against cockroaches and beans weevils.
机译：本研究旨在探索生物效应的化合物分离大戟属植物poissoni pax的配方失能性毒剂对白鼠;将作为一个本土的武器吗尼日利亚国防系统也是一个杀虫剂。poissoni pax受到初步的植物化学的筛选确定存在酚类化合物、生物碱、皂苷和萜类化合物。光谱、气相色谱光谱法(gc - ms)分析表明存在一些化合物包括((4) - 4-Hydroxyphenyl 4-methyl-2-pentanone)三甲基硅烷基醚、棕榈酸、碳酸(lR) -(-)薄荷基壬酯、13-Octadecenoic酸甲酯,1、3、5-triazine、2-chloro-4 6-bis (mthylthio)和邻苯二甲酸,6-ethyloct-3-yl-2-ethylhexyl酯。植物提取物被计算为1733.33毫克/公斤,在经合组织(组织的经济合作与发展组织)的指导方针。提取产生了强大的生物活性在1000毫克/公斤压力下应用河鼠鼠皮肤和丧失2分钟。提取显示有效的杀虫效应对蟑螂和豆类象鼻虫。

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