In Vitro Cytotoxic Effects of Muntingia Calabura Linn. Fruits against Human Cancer Cell Lines

Xiaoya Li

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In Vitro Cytotoxic Effects of Muntingia Calabura Linn. Fruits against Human Cancer Cell Lines

机译：Muntingia calabura Linn的体外细胞毒性作用。针对人类癌细胞系的水果

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This study was designed to evaluate in vitro cytotoxicity of methanol extract of Muntingia calabura Linn. (Elaeocarpaceae) fruits against human cervical cancer cell line (HeLa), human laryngeal epithelial carcinoma cells (Hep-2) and mouse embryonic fibroblasts (NIH 3T3). The cytotoxicity was assessed using the MTT assay. The methanol extract displayed remarkable cytotoxic activity against the cell lines with IC_(50) Values of 1.0 and 0.8 and μg/ml against HeLa, Hep-2 and NIH 3T3 cell lines respectively. The results obtained from the study suggest that the methanol extract tested may be a useful chemotherapeutic agent to inhibit the growth of carcinoma cells and this study would bring light to carry out further experiments and to prevent the cancer in humans.

机译：本研究旨在评估在体外细胞毒性Muntingia的甲醇提取物人类宫颈癌细胞系(海拉),人类喉上皮癌(Hep-2)和细胞小鼠胚胎成纤维细胞(NIH 3 t3)。用MTT测定细胞毒性进行评估。甲醇提取显示显著细胞毒性活动对细胞系IC_(50)值的1.0和0.8μg / ml海拉,分别Hep-2和NIH 3 t3细胞线。研究表明,获得的结果甲醇提取测试可能是有用的化学治疗剂抑制的增长癌细胞,本研究将光开展进一步的实验和预防在人类癌症。

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《International journal of biotechnology and bioengineering research》 |2022年第1期|61-66|共6页
作者
Xiaoya Li;
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作者单位

Xi'an 710127, China;

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原文格式 PDF
正文语种英语
中图分类生物科学;
关键词
Muntingia calabura; cytotoxicity; HeLa; Hep-2; mouse embryonic fibroblast;

机译：麝香;细胞毒性;嘿啦;Hep-2;小鼠胚胎成纤维细胞;

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In Vitro Cytotoxic Effects of Muntingia Calabura Linn. Fruits against Human Cancer Cell Lines

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