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首页> 外文期刊>Journal of the American Animal Hospital Association >Efficacy of a Silver-Based Shampoo for Treatment of Canine Malassezia: A Pilot Study
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Efficacy of a Silver-Based Shampoo for Treatment of Canine Malassezia: A Pilot Study

机译：银基洗发水治疗犬马拉色菌病的功效：一项初步研究

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摘要

Malassezia pachydermatis is a commensal of canines associated with Malassezia dermatitis. Consensus guidelines rec-ommend topical and/or systemic treatment, but resistance to antifungals has been reported. The objective of this pilot study was to determine the efficacy of a 0.003% colloidal silver nanoparticle-based shampoo in the treatment of canine Malassezia dermatitis. Dogs were included based on compatible history, presentation, and at least one positive cytology. Fourteen privately owned dogs were bathed every 48 hr for up to 28 days, allowing 5-10 min of contact time. The mean Malassezia organisms for 10 oil immersion fields at each Malassezia dermatitis-affected body area was recorded at days 0 and 14. Dogs positive on day 14 had cytologies performed on day 28. Eleven dogs (78.6%) were cytologically negative by day 28. Nine (81.8%) of these were negative by day 14. One dog (7.14%) had partial resolution (negative in 3/4 Malas-sezia dermatitis areas) by day 28. These results suggest that silver nanoparticle-based shampoo may be effective in the treatment of canine Malassezia dermatitis. Larger, controlled studies are needed to further investigate efficacy, optimal concentration, and ideal application frequency. (J Am Anim Hosp Assoc 2023; 59:7-11. DOI 10.5326/JAAHA-MS-7286)
机译：细胞死亡pachydermatis是狗的共生体与细胞死亡皮炎有关。指导方针rec-ommend局部和/或系统治疗,但一直抵抗抗真菌治疗报道。确定0.003%的胶体的功效银nanoparticle-based洗发水治疗犬细胞性皮炎。包括基于兼容的历史,表示,至少有一个积极的细胞学。十四民营狗洗一次48小时28天,允许5 - 10分钟接触的时间。在每个细胞死亡10油浸字段被记录在dermatitis-affected身体区域天0和14。细胞学表现在28天。正常值(78.6%)- 28天。9(81.8%)这些都是负面的第14天。一条狗(7.14%)部分决议(负的白天在3/4 Malas-sezia皮炎地区)28。这些结果表明,银nanoparticle-based洗发水可能是有效的犬类细胞性皮炎的治疗。大,研究需要进一步控制调查效果,最佳浓度理想的应用频率。

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