• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of the American Animal Hospital Association >Lung Lobectomy as an Adjunctive Treatment for Refractory Pulmonary Coccidioidomycosis in a Dog
【24h】

Lung Lobectomy as an Adjunctive Treatment for Refractory Pulmonary Coccidioidomycosis in a Dog

机译：肺叶切除术作为狗难治性肺球孢子菌病的辅助治疗

获取原文
获取原文并翻译 | 示例
       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

A 5 yr old, castrated male, border collie mixed-breed dog was evaluated for cough and subsequently diagnosed with pulmonary coccidioidomycosis. Baseline serum anti-Coccidioides spp. immunoglobulin M and immunoglobulin G antibody titers were negative and 1:8, respectively. Thoracic computed tomography identified marked gravity-dependent pulmonary consolidation of the right middle lung lobe and marked tracheobronchial lymphadenomegaly. First-line antifungals were prescribed without adequate clinical orradiographic improvement, and a right middle lung lobectomy was subsequently performed 5.5 mo after diagnosis. Clinical signs associated with the respiratory tract resolved postoperatively. Fluconazole was discontinued 204 days after surgery because thedog remained subclinical, the thoracic computed tomography revealed near normal imaging with the exception of changes typical following a lung lobectomy, and the serum anti-Coccidioides spp. immunoglobulin G titer was 1:2. The dog remained subclinical >90 days after cessation of fluconazole. This case report describes the successful treatment outcome in a dog with severe Coccidioides spp. pneumonia following lung lobectomy and oral antifungal therapy. Future studies are warranted to determine the utility of adjunctive lung lobectomy in dogs with coccidioidomycosis who have large fungal burdens localized to a single lung lobe and are refractory to standard first-line oral antifungal therapies.
机译：一个5岁,被阉割的雄性,边境牧羊犬混血狗咳嗽和评估后来被诊断为肺球孢子菌病。anti-Coccidioides种虫害免疫球蛋白M和免疫球蛋白G抗体滴度为负分别和1:8。断层扫描识别标记gravity-dependent肺整合正确的肺叶,气管支气管的lymphadenomegaly。规定没有足够的临床orradiographic改进,正确的中间肺段切除随后执行5.5后诊断。术后呼吸道解决。氟康唑是停止后204天手术,因为可怜的仍然是亚临床的胸部计算机断层扫描显示接近正常成像除了典型的变化肺段切除后,血清anti-Coccidioides种虫害免疫球蛋白G效价1:2。停止氟康唑。描述了成功的治疗结果狗有严重球孢子菌属种虫害肺炎后肺切除和口服抗真菌治疗。确定辅助肺的效用叶切除术与球孢子菌病狗有一个大型真菌负担本地化吗肺叶,耐火材料标准一线口服抗真菌治疗。

著录项

相似文献

  • 外文文献
  • 中文文献
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号