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Radioprotective Mechanisms of Arbutin: A Systematic Review

机译：Radioprotective Mechanisms of Arbutin: A Systematic Review

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Purpose: Efforts to produce radioprotective agents of high potential are appropriate strategies for overcoming possible IR toxicity in organisms. The present research aims to evaluate the signaling pathways and mechanisms through which arbutin exerts radioprotective effects on organisms. Methods: The databases of PubMed, Web of Sciences, Google Scholar, and Scopus were searched to find studies that reported radioprotective effects for arbutin. Besides, the data were searched within the time period from 2010 to 2020. Results: Five research articles met our criteria, which were included in the analysis based on their relevance to the topic. The present systematic review provides conclusions about various mechanisms and pathways through which arbutin induces radioprotection. Conclusions: Based on the relevant studies, various mechanisms can be proposed for inducing radioprotective effects by arbutin, including inhibition of oxidative stress, apoptosis, and inflammation.
机译：目的:努力产生辐射防护剂高潜力的适当的策略克服可能的红外光谱在生物毒性。目前的研究旨在评估信号熊果苷的途径和机制对辐射防护对生物体的影响。方法:PubMed数据库的Web科学、谷歌学者和斯高帕斯搜索找到的研究报道熊果苷的放射防护作用。数据搜索的时间段内2010年到2020年。我们的标准,包括在分析中基于它们与主题的相关性。目前系统评价提供的结论关于各种机制和途径熊果苷诱导辐射防护。结论:根据相关研究,可以提出了诱导各种机制熊果苷放射防护效果,包括抑制氧化应激、细胞凋亡和炎症。

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