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首页> 外文期刊>International wound journal. >Effectiveness of skin cleanser and protectant regimen on incontinence-associated dermatitis outcomes in acute care patients: A cluster randomised trial
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Effectiveness of skin cleanser and protectant regimen on incontinence-associated dermatitis outcomes in acute care patients: A cluster randomised trial

机译：皮肤清洁剂和保护剂方案对急症护理患者尿失禁相关性皮炎结局的有效性：一项整群随机试验

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Skin cleansers and protectants protect skin from incontinent matter to reduce the risk of incontinence-associated dermatitis (IAD), but their effectiveness treating established IAD in the tropics is unknown. We conducted an open-label cluster randomised trial to compare the effectiveness of a combined regimen of (1) specialised skin cleansers with disposable body wipes and (2) either an acrylic terpolymer (T1) or zinc oxide (T2) skin protectant against disposable body wipes and zinc oxide protectant (control) in promoting IAD healing and reducing the risk of deterioration. Eighty-four patients were recruited in a tertiary hospital in Singapore between April 2019 and January 2020 (T1: n = 23; T2: n = 37; Control: n = 24). Although not statistically significant, patients treated with T1 and T2 were 1.5 times as likely to experience IAD healing within seven days compared with the control (P = .66). Healing was more pronounced in participants with skin loss treated with T1 or T2. No treatment was superior in preventing IAD deterioration, the prevalence of which remained small (8%-14%). While skin cleaning and protectants reduced the overall risk of skin deterioration, the addition of skin cleansers enhanced IAD healing within a short period, an important consideration for future research examining IAD treatment in acute care.
机译：皮肤清洁剂和保护剂可保护皮肤免受失禁物质的侵害，以降低失禁相关性皮炎 （IAD） 的风险，但它们在热带地区治疗已确诊 IAD 的有效性尚不清楚。我们进行了一项开放标签整群随机试验，以比较 （1） 专用皮肤清洁剂与一次性身体湿巾和 （2） 丙烯酸三元共聚物 （T1） 或氧化锌 （T2） 皮肤保护剂与一次性身体湿巾和氧化锌保护剂（对照）的联合方案在促进 IAD 愈合和降低恶化风险方面的有效性。2019 年 4 月至 2020 年 1 月期间，在新加坡一家三级医院招募了 84 名患者（T1：n = 23;T2：n = 37;对照：n = 24）。虽然没有统计学意义，但与对照组相比，接受 T1 和 T2 治疗的患者在 7 天内经历 IAD 愈合的可能性是 1.5 倍 （P = .66）。在接受 T1 或 T2 治疗的皮肤损失参与者中，愈合更为明显。在预防IAD恶化方面，没有一种治疗方法优于IAD，其患病率仍然很小（8%-14%）。虽然皮肤清洁和保护剂降低了皮肤恶化的总体风险，但添加皮肤清洁剂可在短时间内促进 IAD 愈合，这是未来研究急性护理中 IAD 治疗的重要考虑因素。

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