High‐Throughput Combinatorial Synthesis of Stimuli‐Responsive Materials

Rosenfeld Alisa; Levkin Pavel A.

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High‐Throughput Combinatorial Synthesis of Stimuli‐Responsive Materials

机译：High‐Throughput Combinatorial Synthesis of Stimuli‐Responsive Materials

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Abstract Stimuli‐responsive materials find wide applications in different biological and medical settings. Traditionally, stimuli‐responsive materials are synthesized and evaluated individually one‐by‐one. The drawback of this approach is the scarceness of possible combinations that can be practically tested for the purpose of saving time, consumables, and manpower. High‐throughput methods are therefore important to accelerate the discovery of stimuli‐responsive materials and to screen for biological interactions of interest in parallel. The objective of this article is to provide an overview of the successful employment of combinatorial high‐throughput synthesis and screening of stimuli‐responsive materials. In particular, these include thermoresponsive and hydroresponsive materials. Advantages of a combinatorial approach as well as of utilizing high‐throughput methodologies in the development of stimuli‐responsive materials are reviewed. Possible evolution trends of stimuli‐responsive materials, advanced by high‐throughput methodologies, are discussed.

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《Advanced Biosystems》 |2019年第3期|n/a-n/a|共8页
作者
Rosenfeld Alisa; Levkin Pavel A.;
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作者单位

Institute of Toxicology and GeneticsKarlsruhe Institute of Technology76344,Eggenstein‐Leopoldshafen,Germany;

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原文格式 PDF
正文语种英语
中图分类生物科学;
关键词
combinatorial libraries; high‐throughput synthesis; material microarrays; smart materials; stimuli‐responsive;

High‐Throughput Combinatorial Synthesis of Stimuli‐Responsive Materials

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