Acute toxicity studies on aqueous extract of stem bark of Butyrospermum paradoxum in rats

J. S. RABO; P. A. ONYEYILI; M. A. SALAKOM. I. KHALIL

首页> 外文期刊>Bulletin of Animal Health and Production in Africa >Acute toxicity studies on aqueous extract of stem bark of Butyrospermum paradoxum in rats

【24h】

Acute toxicity studies on aqueous extract of stem bark of Butyrospermum paradoxum in rats

机译：Acute toxicity studies on aqueous extract of stem bark of Butyrospermum paradoxum in rats

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相关主题

摘要

Aqueous extract of stem bark Butyrospermum paradoxum was tested for acute toxicity in rats; the intraperitoneal LD_(50) of the extract was found to be 240mg/kg. The manifestation of clinical signs was dose related. At high doses all the rats became markedly dehydrated, weak, depressed, anorexic and had difficulty in respiration before death; while at low doses they developed mild depression, respiratory difficulty and anorexia. Nephritis with tubular degeneration and necrosis were noticed in the kidneys of all dead rats, while fatty degeneration with necrosis and pulmonary congestion and oedema were noticed in the liver and lungs respectively. These findings indicated that the stem bark of B. paradoxum is highly toxic and should be used with caution in folklore medicine.

著录项

来源
《Bulletin of Animal Health and Production in Africa》 |2000年第1期|39-43|共5页
作者
J. S. RABO; P. A. ONYEYILI; M. A. SALAKOM. I. KHALIL;
展开▼
作者单位

Department of Veterinary Pathology, University of Maiduguri, P.M.B. 1069, Maiduguri, Borno State, Nigeria;

展开▼
收录信息
原文格式 PDF
正文语种英语
中图分类 S8 畜牧、动物医学、狩猎、蚕、蜂;
关键词
toxicity; Butyrospermum paradoxum in rat; pasture; medicinal plants;

Acute toxicity studies on aqueous extract of stem bark of Butyrospermum paradoxum in rats

摘要

著录项

相关主题

期刊订阅