PRC2 activity, recruitment, and silencing: a comparative perspective

Bieluszewski Tomasz; Xiao Jun; Yang YimanWagner Doris

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PRC2 activity, recruitment, and silencing: a comparative perspective

机译：PRC2 activity, recruitment, and silencing: a comparative perspective

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Polycomb repressive complex (PRC)-mediated gene silencing is vital for cell identity and development in both the plant and the animal kingdoms. It also modulates responses to stress. Two major protein complexes, PRC1 and PRC2, execute conserved nuclear functions in metazoans and plants through covalent modification of histones and by compacting chromatin. While a general requirement for Polycomb complexes in mitotically heritable gene repression in the context of chromatin is well established, recent studies have brought new insights into the regulation of Polycomb complex activity and recruitment. Here, we discuss these recent advances with emphasis on PRC2.

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《Trends in Plant Science》 |2021年第11期|1186-1198|共13页
作者
Bieluszewski Tomasz; Xiao Jun; Yang YimanWagner Doris;
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Univ Penn, Dept Biol, Philadelphia, PA 19103 USA;

Chinese Acad Sci, Innovat Acad Seed Design, Inst Genet & Dev Biol, State Key Lab Plant Cell & Chromosome Engn, Beijing 100101, Peoples R China;

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正文语种英语
中图分类植物学;
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PRC2 activity, recruitment, and silencing: a comparative perspective

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