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首页> 外文期刊>Quality of life research: An international journal of quality of life aspects of treatment, care and rehabilitation >Disparities in women’s cancer-related quality of life by Southern Appalachian residence
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Disparities in women’s cancer-related quality of life by Southern Appalachian residence

机译:Disparities in women’s cancer-related quality of life by Southern Appalachian residence

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Purpose The purpose was to determine whether Appalachian residence alone or in combination with violence was linked to poorer quality of life (QOL). Methods Women recently diagnosed and included in either the Kentucky or North Carolina Cancer Registries were interviewed by phone between 2009 and 2015 ( n ?=?3320; mean age?=?56.74). Response rates were similar by state (40.1 in Kentucky and 40.9% in North Carolina). Appalachian ( N ?=?990) versus non-Appalachian residents ( N ?=?2330) were hypothesized to have poorer QOL defined as (a) lower Functional Assessment of Cancer Therapy—General (FACT-G) scores and (b) more symptoms of depression, stress, or comorbid physical conditions. Lifetime intimate partner or sexual violence was first investigated as a moderator then mediator of regional differences. Multiple analyses of covariance (MANCOVA) models were used. Results Violence modified the effect of Appalachian residence on poorer QOL outcomes; FACT-G total scores ( p ?=?.02) were lowest for women living in Appalachia who had additionally experienced violence. Socioeconomic indicators appeared to mediate or explain differences in QOL outcomes by Appalachian residence such that when adjusting for income, education and insurance, Appalachian residence remained associated only with poorer physical QOL outcomes ( p ?

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