Post marketing surveillance on safety and efficacy of IMOD in iranian patients with HIV/AIDS

MohrazM.; SedaghatA.; SeyedAlinaghiS.A.AsheriH.MohammaddoustS.GharibdoostF.KhorshidH.R.K.FarhadiM.MadaniS.H.KamaliK.

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Post marketing surveillance on safety and efficacy of IMOD in iranian patients with HIV/AIDS

机译：Post marketing surveillance on safety and efficacy of IMOD in iranian patients with HIV/AIDS

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Acquired Immune Deficiency Syndrome is one of the world's serious health problems. Immune-based therapy is a new approach in the treatment of HIV infected patients. IMOD? with the ability to correct immune deficiencies has been introduced for the management of HIV infection. In the phase IV trial study the main objectives were to assess the possible side effects, evaluate its effect on CD4+ T Lymphocyte count and patients' and physicians' satisfactions for 600 HIV infected patients in 13 centers during 2007. The observed adverse events in patients included: headache and vertigo (1.2%), nausea (1.2%), gastritis (1.2%), phlebitis (1%) and mild rash (1%); serious adverse events were not observed in any of IMOD? recipients. Therefore it was not needed to terminate the treatment in any of patient. The results of this study demonstrated that daily prescription of IMOD? significantly increases T Lymphocyte CD4+ and Total Lymphocyte Count in HIV-positive patients. In addition, nearly 90% of the patients and 70% physicians are satisfied by IMOD? treatment.

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《Infectious disorders drug targets》 |2013年第1期|71-74|共4页
作者
MohrazM.; SedaghatA.; SeyedAlinaghiS.A.AsheriH.MohammaddoustS.GharibdoostF.KhorshidH.R.K.FarhadiM.MadaniS.H.KamaliK.;
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作者单位

Iranian Research Center for HIV/AIDS, Tehran University of Medical Sciences, Tehran, Iran;

Ministry of Health and Medical Education, Iran;

Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, IranGenetic Research Centre, University of Social Welfare and Rehabilitation Sciences, Tehran, IranHead and Neck Surgery Division, Tehran University of Medical Sciences, Tehran, IranDepartment of Biotechnology, Rabe Rashidi Institute, Tabriz, IranReproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran;

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正文语种英语
中图分类药学;
关键词
Efficacy; IMOD?; Post marketing surveillance; Safety; Satisfaction; Side effect;

Post marketing surveillance on safety and efficacy of IMOD in iranian patients with HIV/AIDS

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