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Polarographic behavior of the β‐lactam antibioticCefuroximeand study of the reduction mechanism in acidic media

机译:Polarographic behavior of the β‐lactam antibioticCefuroximeand study of the reduction mechanism in acidic media

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AbstractPolarographic behavior of the cephalosporin Cefuroxime (CFXN) in aqueous solutions of PH ranging from 1 to 10 was investigated. The reactant is strongly adsorbed in acidic media, while in neutral and alkaline solution, electrode reaction is not affected by adsorption phenomena. A kinetic study of the methoxyimino group electroreduction to methanol and an aminic derivative in acidic media was carried out. The overall electrode process is controlled by the heterogeneous protonation step preceded by a fast electronation step in the pH range 1 to 3, whereas for 3

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