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Evaluating post-vaccine expansion patterns of pneumococcal serotypes

机译:Evaluating post-vaccine expansion patterns of pneumococcal serotypes

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摘要

Background: Streptococcus pneumoniae remains a leading cause of morbidity and mortality. Pneumococcal conjugate vaccines (PCVs) are effective but target only a fraction of the more than 90 pneumococcal serotypes. As a result, the introduction of PCVs has been followed by the emergence of non-vaccine serotypes. With higher-valency PCVs currently under development, there is a need to understand and predict patterns of serotype replacement to anticipate future changes.

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