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首页> 外文期刊>Infectious disorders drug targets >Hepatitis A Seroprevalence Among Patients with Chronic Hepatitis B Infection: A Cross-Sectional Study in Iran During 2016-2017 Bentham Science
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Hepatitis A Seroprevalence Among Patients with Chronic Hepatitis B Infection: A Cross-Sectional Study in Iran During 2016-2017 Bentham Science

机译：Hepatitis A Seroprevalence Among Patients with Chronic Hepatitis B Infection: A Cross-Sectional Study in Iran During 2016-2017 Bentham Science

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Introduction: The aim of this study was to determine the prevalence of exposure tohepatitis A by means of serologic markers in chronic hepatitis B patients, with the secondary aimof finding the best prevention method for hepatitis A infection in susceptible groups of our setting.Methods: During the period between 2016 and 2017, we recruited 403 hepatitis B patients agedmore than 14 years and regularly attending the infectious diseases clinic at a referral universityhospital, Tehran, Iran. A blood sample was collected from all the patients and tested for hepatitisA IgG. The data was analyzed by SPSS v.19.Results: Although none of the patients had previously received hepatitis A vaccine, the results forserologic level of hepatitis A IgG, demonstrated positive results in 379 (94%) cases. The meanage of patients with negative and positive IgG was 29.17 and 42.46 years, respectively; the differencewas statistically significant (P≤0.001). The majority of seronegative patients were youngadults aged < 25 years and 25 to 35 years (P <0.001).Conclusion: Seroprevalence of hepatitis A in chronic HBV patients in Iran is high. As HBV infectedpatients younger than 35 years could be seronagative for HAV infection, evaluation ofthese patients for HAV infection and vaccination of seronegative patients would be a reasonableapproach.

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