Structural and Functional Adaptive Artificial Bone: Materials, Fabrications, and Properties

Pei Feng; Rongyang Zhao; Weiming TangFeng YangHaifeng TianShuping PengHao PanCijun Shuai

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Structural and Functional Adaptive Artificial Bone: Materials, Fabrications, and Properties

机译：Structural and Functional Adaptive Artificial Bone: Materials, Fabrications, and Properties

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摘要

It is an urgent need that defect repair can develop from simple device fixationto living tissue reconstruction, from short life function replacement topermanent regeneration repair. At present, bone transplantation has becomethe second largest transplantation surgery after blood transfusion, andartificial bone transplantation generates great hope for the repair and treatmentof bone defect. In order to repair bone defect, artificial bone must havegood biological properties and sufficient mechanical properties, and it shouldalso have the shape matching to bone defect site and the connected porousstructure. For structures and properties requirements of artificial bone, inthis review three major challenges faced by artificial bone transplantation aresystemtically analyzed and current methods and strategies to address theseissues are discussed: 1) the need for developing a type of bone scaffold materialwith both biological and mechanical properties, 2) the need for realizingthe controllable fabrication of individual shape and multistage pore structureof bone scaffold, 3) the need for realizing the transformation from man-madestructure to biological structure. Besides, it summarizes the advantages anddisadvantages of these methods and discusses the potential future directionsof structural and functional adaptive artificial bone for bone defectregeneration.

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来源
《Advanced functional materials》 |2023年第23期|2214726.1-2214726.29|共29页
作者
Pei Feng; Rongyang Zhao; Weiming TangFeng YangHaifeng TianShuping PengHao PanCijun Shuai;
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作者单位

NHC Key Laboratory of Carcinogenesis of Hunan Cancer Hospital andthe Affiliated Cancer Hospital of Xiangya School of MedicineCancer Research Institute, School of Basic Medical ScienceCentral South UniversityChangsha 410013, China The Key Laboratory of Car;

Department of Periodontics & Oral Mucosal SectionXiangya Stomatological Hospital & Xiangya School of StomatologyCentral South UniversityChangsha 410013, China;

State Key Laboratory of High Performance Complex ManufacturingCollege of Mechanical and Electrical EngineeringCentral South UniversityChangsha 410083, China Institute of Additive ManufacturingJiangxi University of Science and TechnologyNanchang 330013, ChState Key Laboratory of High Performance Complex ManufacturingCollege of Mechanical and Electrical EngineeringCentral South UniversityChangsha 410083, China;

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正文语种英语
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关键词
artificial bones; bone regeneration; fabrication methods; materials; properties;

Structural and Functional Adaptive Artificial Bone: Materials, Fabrications, and Properties

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