In this issue of the Journal of Clinical Monitoring and Computing, Giraud et al. investigated the impact of hypovolemia on the respiratory variations in the QRS amplitude on a classical DII EKG lead (ARDII) [1]. In this animal study, they were able to demonstrate that bleeding and volume expansion induced significant changes in ARDII and that these changes mirrored those observed in the respiratory variations in pulse pressure (PPV). These observations suggest that this non-invasive and potentially widely available parameter could predict fluid responsiveness and detect hypovolemia in operating rooms and intensive care units.
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