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首页> 外文期刊>international journal of immunogenetics >SUPRAMOLECULAR RELATIONSHIPS OF MEMBRANE ANTIGENS ON THE MURINE THYMOCYTE
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SUPRAMOLECULAR RELATIONSHIPS OF MEMBRANE ANTIGENS ON THE MURINE THYMOCYTE

机译:SUPRAMOLECULAR RELATIONSHIPS OF MEMBRANE ANTIGENS ON THE MURINE THYMOCYTE

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SUMMARYThe topographical relationship of Thy‐1, Ly‐1, Ly‐2, and T200 were examined on the murine thymocyte. The inhibition of the binding of radiolabelled monoclonal antibody after incubation with unlabelled heterologous antibody was used as a measure of the proximity of the target antigens on the cell surface. On unfixed cells, prior incubation with anti‐Thy‐1.2 impeded the attachment of labelled anti‐Ly‐1, anti‐Ly‐2, and anti‐T200. Anti‐T200, but not anti‐Ly‐1, or anti‐Ly‐2, was capable of impeding the attachment of labelled anti‐Thy‐1.2 on unfixed cells. In general, gentle fixation with paraformaldehyde did not alter these inter‐relationships. The possible functional contributions of such supramo

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