• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Russian Journal of Physical Chemistry >Mechanisms of Reactions between Cobalamins and Diethylamine Diazenium Diolate in Neutral Aqueous Solutions
【24h】

Mechanisms of Reactions between Cobalamins and Diethylamine Diazenium Diolate in Neutral Aqueous Solutions

机译：Mechanisms of Reactions between Cobalamins and Diethylamine Diazenium Diolate in Neutral Aqueous Solutions

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相关主题

摘要

Reactions between diethylamine diazenium diolate (DEANONO) and aqua-, methyl-, cyano-, sulfito- and glutathionylcobalamins, cobalamin(II), and aquahydroxocobinamide were studied at pH 7.4 and 25.0 degrees C using ultraviolet-visible spectrometry. Kinetic curves are simulated according to the mechanism proposed in the ChemMech program. It is shown that methyl-, cyano-, and sulfito-cobalamins do not react with DEANONO. The reaction between aquacobalamin and DEANONO does not produce nitrosylcobalamin (NOCbl) because of the relatively rapid decomposition of DEANONO and the slow interaction between the initial reagents. It is established that glutathionylcobalamin is converted into NOCbl due to interaction with nitric oxide released during the decomposition of DEANONO and the transfer of the nitroxyl of DEANONO molecules to Co(III) ions. Cobalamin(II) is converted to NOCbl by the rapid binding of NO released during the decomposition of DEANONO. It is shown that the reaction between aquahydroxocobinamide and DEANONO includes the rapid coordination of DEANONO to Co(III) ions and slower decomposition of the complex into nitrosylcobinamide and other products.

著录项

获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号