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>Interferon induces cell fusion and the formation of multinuclear cells in a culture of ehrlich ascites tumor cells
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Interferon induces cell fusion and the formation of multinuclear cells in a culture of ehrlich ascites tumor cells
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机译:Interferon induces cell fusion and the formation of multinuclear cells in a culture of ehrlich ascites tumor cells
AbstractThe increase in number of Ehrlich ascites tumor (EAT) cells was diminished significantly when the cell culture was treated with 1,000 lU/ml of recombinant mouse alpha or beta interferon (IFN). Microscopical observation revealed that almost all the cells showed bi‐or multinuclear morphology 3 to 5 days after IFN treatment. Furthermore, a videorecording showed that each multinuclear cell arose by fusion after mitotic division of one parental cel
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