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首页> 外文期刊>Bulletin of Animal Health and Production in Africa >The effect of coccidial infection on the reactivity of the smooth muscle of the caeca of domestic chickens (Gallus domesticus) to histamine and carbachol
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The effect of coccidial infection on the reactivity of the smooth muscle of the caeca of domestic chickens (Gallus domesticus) to histamine and carbachol

机译：The effect of coccidial infection on the reactivity of the smooth muscle of the caeca of domestic chickens (Gallus domesticus) to histamine and carbachol

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The contractile responses of caecal segments from healthy and domestic chickens infected with Eimeria tenella on exposure to exogenous carbachol and histamine were studied. Graded molar concentrations of the agonists were introduced into suspensionsof the segments in Tyrode's solution at 37 deg C and the responses recorded. Both healthy and infected segments were sensitive to the agonists. Although the infected segments showed greater sensitivity to the agonists, they produced significantly (P<0.05) lower maximum responses in all cases. While the healthy segments elicited an overall response curve with a sigmoid shape, that of the infected segments was non-sigmoid. It is concluded that coccidial infection of chickens significantly altered the contractile response of caecal segments to carbachol and histamine.

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