Lipid Biomarkers in Alzheimer's Disease

Zarrouk Amira; Debbabi Meryam; Bezine MaryemKarym El MostafaBadreddine AsmaaRouaud OlivierMoreau ThibaultCherkaoui-Malki MustaphaEl Ayeb MohamedNasser BoubkerHammami MohamedLizard Gerard

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Lipid Biomarkers in Alzheimer's Disease

机译：Lipid Biomarkers in Alzheimer's Disease

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Background: There are now significant evidences that lipid metabolism is affected in numerous neurodegenerative diseases including Alzheimer's disease. These dysfunctions lead to abnormal levels of certain lipids in the brain, cerebrospinal fluid and plasma. It is consequently of interest to establish lipid profiles in neurodegenerative diseases. This approach, which can contribute to identify lipid biomarkers of Alzheimers' disease, can also permit to identify new therapeutic targets. It was therefore of interest to focus on central and peripheral biomarkers in Alzheimer's disease.

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《Current Alzheimer research》 |2018年第4期|303-312|共10页
作者
Zarrouk Amira; Debbabi Meryam; Bezine MaryemKarym El MostafaBadreddine AsmaaRouaud OlivierMoreau ThibaultCherkaoui-Malki MustaphaEl Ayeb MohamedNasser BoubkerHammami MohamedLizard Gerard;
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作者单位

Univ Hassan 1Er, Fac Sci & Tech, Lab Biochim & Neurosci, Settat, Morocco;

Univ Monastir, Fac Med, Lab NAFS Nutr Funct Food & Vasc Hlth, LR12ES05, Monastir, Tunisia;

Univ Bourgogne Franche Comte, INSERM, Dept Biochem Peroxisome Inflammat & Lipid Metab, Dijon, FranceUniv Hosp, Memory Ctr, Resources & Res Burgundy, Dijon, FranceUniv Bourgogne Franche Comte, Univ Hosp, Dept Neurol, Dijon, FranceUniv Tunis El Manar, Pasteur Inst, Lab Venoms & Therapeut Biomol, Tunis, Tunisia;

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正文语种英语
中图分类神经病学与精神病学;
关键词
Alzheimer; biomarkers; lipids; cholesterol; oxysterols; fatty acids; phospholipids;

Lipid Biomarkers in Alzheimer's Disease

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