The medicinal chemistry of Chikungunya virus

Edeildo F. da Silva-Júnior; Giovanni O. Leoncini; érica E.S. RodriguesThiago M. AquinoJo?o X. Araújo-Júnior

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The medicinal chemistry of Chikungunya virus

机译：The medicinal chemistry of Chikungunya virus

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Graphical abstract Display Omitted Abstract Arthropod-borne viruses (arboviruses) are an important threat to human and animal health globally. Among these, zoonotic diseases account for billions of cases of human illness and millions of deaths every year, representing an increasing public health problem. Chikungunya virus belongs to the genus Alphavirus of the family Togariridae, and is transmitted mainly by the bite of female mosquitoes of the Aedes aegypti and/or A. albopictus species. The focus of this review will be on the medicinal chemistry of Chikungunya virus, including synthetic and natural products, as well as rationally designed compounds. ]]>

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《Bioorganic and medicinal chemistry》 |2017年第16期|4219-4244|共26页
作者
Edeildo F. da Silva-Júnior; Giovanni O. Leoncini; érica E.S. RodriguesThiago M. AquinoJo?o X. Araújo-Júnior;
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作者单位

Laboratory of Medicinal Chemistry, Nursing and Pharmacy School, Federal University of Alagoas;

Chemistry and Biotechnology Institute, Federal University of Alagoas;

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原文格式 PDF
正文语种英语
中图分类药学;
关键词
Chikungunya; Medicinal chemistry; Synthesis; Natural products; In silico;

The medicinal chemistry of Chikungunya virus

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