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首页> 外文期刊>Chronobiology international >Association between light exposure at night and manic symptoms in bipolar disorder: cross-sectional analysis of the APPLE cohort
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Association between light exposure at night and manic symptoms in bipolar disorder: cross-sectional analysis of the APPLE cohort

机译：Association between light exposure at night and manic symptoms in bipolar disorder: cross-sectional analysis of the APPLE cohort

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Previous studies have found that keeping the room dark at night was associated with a decrease in manic symptoms for patients with bipolar disorder (BD). However, the association between light at night of real-life conditions and manic symptoms is unclear. We investigated the association between bedroom light exposure at night and manic symptoms in BD patients. One-hundred and eighty-four outpatients with BD participated in this cross-sectional study. The average light intensity at night during sleep was evaluated using a portable photometer for seven consecutive nights. Manic symptoms were assessed using the Young Mania Rating Scale (YMRS), and scores >= 5 were treated as a "hypomanic state." The median (interquartile range) YMRS score was 2.0 (0-5.0), and 52 (28.2%) participants were in a hypomanic state. The prevalence of a hypomanic state was significantly higher in the participants with an average light intensity at night exposure of >= 3 lux than in those with = 3 lux than for those with = 6 (OR: 2.51, 95% confidence interval: 1.15-5.46; P = .02). The findings of this study indicate bedroom light exposure at night is significantly associated with manic symptoms in BD patients. Although the results of this cross-sectional investigation do not necessarily imply causality, they may serve to inform beneficial nonpharmacological intervention and personalized treatment of BD patients.

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