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首页> 外文期刊>Electroanalysis >Detection of Dexamethasone Sodium Phosphate in Blood Plasma: Application of Hematite in Electrochemical Sensors
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Detection of Dexamethasone Sodium Phosphate in Blood Plasma: Application of Hematite in Electrochemical Sensors

机译：Detection of Dexamethasone Sodium Phosphate in Blood Plasma: Application of Hematite in Electrochemical Sensors

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摘要

We studied sensor application of a graphene oxide and hematite (alpha-Fe2O3/GO) composite electrode well-characterized by the SEM and XRD. Through differential pulse voltammetry (DPV), oxidation of dexamethasone sodium phosphate (DSP) was studied at the surface of a glassy carbon electrode (GCE) modified with graphene oxide nanosheets (GO) and the alpha-Fe2O3/GO composite. The values of the transfer coefficient (alpha) and the diffusion coefficient (D) of DSP were 0.5961 and 4.71x10(-5) cm(2) s(-1) respectively. In the linear range of 0.1-50 mu M, the detection limit (DL) was 0.076 mu M. In the second step, a GCE was modified with alpha-Fe2O3/GO composite and the DSP measurement step was repeated to analyzed and compare the effects of hematite nanoparticles present on graphene oxide surfaces. According to the results, alpha and D were 0.52 and 2.406x10(-4) cm(2) s(-1) respectively and the DL was 0.046 mu M in the linear range of 0.1-10.0 mu M. The sensor is simple, inexpensive and uses blood serum.

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