Prostaglandin F2αwas infused into 13 nonpregnant volunteers at a rate of 50 μg/minute for 8 hours. Ten subjects had a shortened Iuteal phase. Nine subjects had decreased progesterone values at 8 hours, ranging from 23.5 to 69.8% of baseline values. No consistent changes in plasma estradiol or estrone were noted. The significance of these findings is discussed.
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