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首页> 外文期刊>journal of cellular physiology >Amiloride‐dependent transport is the main mechanism implicated in sodium iinflux regulation in rat mast cells
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Amiloride‐dependent transport is the main mechanism implicated in sodium iinflux regulation in rat mast cells

机译：Amiloride‐dependent transport is the main mechanism implicated in sodium iinflux regulation in rat mast cells

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AbstractMast cell sodium regulation is a largely unknown field. In our effort to study the mechanisms by which mast cells regulate sodium levels, we have examined the effect of amiloride and ouabain on22Na entry in rat mast cells in isotonic and hypertonic conditions. Ouabain (0.5 mM) enhances sodium uptake by 32% in isotonic conditions. Hypertonicity increases by 400% the uptake of sodium through an amiloride (1 mM) dependent mechanism. Ouabain has no appreciable effect on the entry of22Na in hypertonic conditions. © 1993 Wiley‐Liss, I

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