Cataract in children and adolescents with type 1 diabetes. Insights from the German/Austrian DPV registry

Ursula M. Reiter; Alexander J. Eckert; Desiree DunstheimerSusanne Bechtold‐Dalla PozzaCaroline LüllwitzSven GolembowskiMarkus FreffSilke HerrlingerThekla von dem BergeMirko RehbergEggert LilienthalReinhard W. Holl

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Cataract in children and adolescents with type 1 diabetes. Insights from the German/Austrian DPV registry

机译：Cataract in children and adolescents with type 1 diabetes. Insights from the German/Austrian DPV registry

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Abstract Objective To study diabetic cataract in type 1 diabetes in a large pediatric cohort. Methods The 92,633 patients aged 0.5–21?years from German/Austrian multicenter diabetes registry (DPV) were analyzed. The 235 patients (0.25%) with diabetic cataract were found, 200 could be categorized: 67 with early cataract (3?months before diabetes onset ‐ 12?months afterwards), 133 with late cataract (>12?months after diabetes onset). Regression models adjusted for age and gender were used to compare clinical parameters at diabetes onset. Regression models for patients with late cataract were implemented for the total documentation period and additionally adjusted for diabetes duration. Results Rate of cataract development shows a peak at diabetes onset and declines with longer diabetes duration. Patients with cataract showed strong female preponderance. Patients developing early cataract were older at diabetes onset (12.8?years [11.8/13.9] vs. 8.9 [8.9/9.0]; p?

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《Pediatric diabetes.》 |2022年第3期|362-369|共8页
作者
Ursula M. Reiter; Alexander J. Eckert; Desiree DunstheimerSusanne Bechtold‐Dalla PozzaCaroline LüllwitzSven GolembowskiMarkus FreffSilke HerrlingerThekla von dem BergeMirko RehbergEggert LilienthalReinhard W. Holl;
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Institute of Epidemiology and Medical Biometry, ZIBMT, University of Ulm, Ulm, Germany;

German;

Department of Pediatrics,University Children's Hospital Augsburg;

Pediatric Endocrinology and Diabetology, iSPZ, Haunersche Kinderklinik,Ludwig‐Maximilians‐UniversityDepartment of Pediatrics,University Hospital MagdeburgDepartment of Pediatrics,Sana Hospital LichtenbergDepartment of Pediatrics,Kinderkliniken Prinzessin MargaretDepartment of Pediatrics,Klinikum Bremen NordDiabetes Centre for Children and Adolescents,Children's Hospital Auf der BultDepartment of Pediatrics,University of Cologne, Faculty of Medicine and University Hospital CologneDepartment of Pediatrics,University Hospital St. Josef Bochum;

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正文语种英语
中图分类儿科学;
关键词
cataract; diabetes complications; glycemic control; lens; type 1 diabetes;

Cataract in children and adolescents with type 1 diabetes. Insights from the German/Austrian DPV registry

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