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>A novel series ofO,O‐diethylO‐(1,3‐disubstituted‐1,2,4‐triazol‐5‐yl) phosphorothioates. Part II. Quantitative structure–activity relationships
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A novel series ofO,O‐diethylO‐(1,3‐disubstituted‐1,2,4‐triazol‐5‐yl) phosphorothioates. Part II. Quantitative structure–activity relationships
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机译：A novel series ofO,O‐diethylO‐(1,3‐disubstituted‐1,2,4‐triazol‐5‐yl) phosphorothioates. Part II. Quantitative structure–activity relationships
AbstractThe in‐vivo toxicity data of 33O,O‐diethylO‐(1‐alkyl‐3‐R″‐1,2,4‐triazol‐5‐yl) phosphorothioates, reported in Part I of this series, were subjected to multiregression analyses for the following organisms:Leptinotarsa decemlineata(larvae),Macrosiphum euphorbiae(aphids),Culex pipiens(adults),Spodoptera littoralis(larvae) and the rat. The activities were found to depend mainly on the steric parameters of R″, these being best expressed by the values L, B1and B4of the computer program STERIMOL. It was shown that there were different steric requirements for each species and these are discussed. The predictive values of the best equati
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