A New Comparative Potentiometric Method for Analysis of Omarigliptin Using Three Different Sensors

Kelani Khadiga M.; Hegazy Maha A.; Hassan Amal M.Tantawy Mahmoud A.

首页> 外文期刊>Electroanalysis >A New Comparative Potentiometric Method for Analysis of Omarigliptin Using Three Different Sensors

【24h】

A New Comparative Potentiometric Method for Analysis of Omarigliptin Using Three Different Sensors

机译：A New Comparative Potentiometric Method for Analysis of Omarigliptin Using Three Different Sensors

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相关主题

摘要

This work represents first attempt for potentiometric determination of the most recent antidiabetic; omarigliptin. Three sensors, employing potassium tetrakis (p-chlorophenyl) borate as a lipophilic cation exchanger, were developed and compared. One liquid contact ionselective electrode and two carbon paste-based solid contact ones, plain one and another one modified with polyaniline nanoparticles, were employed. Performances of fabricated sensors were assessed as per IUPAC recommendations. Incorporation of hydrophobic polyaniline nanoparticles as ion-to-electron transducer layer at solid contact/ion-sensitive membrane interface enhanced sensitivity and stability of the third sensor showing LOD of 2.5x10(-7) molL(-1) and slope of 58.57 mV decade(-1). The three sensors were applied for omarigliptin determination in presence of its degradation products, in dosage form and spiked human plasma.

著录项

来源
《Electroanalysis》 |2023年第1期|302-307|共6页
作者
Kelani Khadiga M.; Hegazy Maha A.; Hassan Amal M.Tantawy Mahmoud A.;
展开▼
作者单位

Cairo Univ;

October 6 Univ;

展开▼
收录信息
原文格式 PDF
正文语种英语
中图分类电化学、电解、磁化学;
关键词
Omarigliptin; Ion-Selective electrode; Polyaniline nanoparticles; Human plasma; Potentiometry; ION-SELECTIVE ELECTRODES; POLYANILINE NANOPARTICLES; CONDUCTING POLYMER; CARBON NANOTUBES; PASTE ELECTRODE;

A New Comparative Potentiometric Method for Analysis of Omarigliptin Using Three Different Sensors

摘要

著录项

相关主题

期刊订阅