SARS‐CoV‐2 vaccines: A double‐edged sword throughout rapid evolution of COVID‐19

Mohammad Ali Zolfaghari; Farzaneh Ghadiri Moghaddam; Shabnam RajputAbbas KarimiMohadeseh Naghi VishtehAta MahmoodpoorSanam DolatiMehdi Yousefi

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SARS‐CoV‐2 vaccines: A double‐edged sword throughout rapid evolution of COVID‐19

机译：SARS‐CoV‐2 vaccines: A double‐edged sword throughout rapid evolution of COVID‐19

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Abstract After more than 2 years of the coronavirus disease 2019 pandemic caused by severe acute respiratory syndrome coronavirus 2, several questions have remained unanswered that affected our daily lives. Although substantial vaccine development could resist this challenge, emerging new variants in different countries could be considered as potent concerns regarding the adverse effects of reinfection or postvaccination. Precisely, these concerns address some significant and probable outcomes in vaccinated or reinfected models, followed by some virus challenges, such as antibody‐dependent enhancement and cytokine storm. Therefore, the importance of evaluating the effectiveness of neutralizing antibodies (nAbs) elicited by vaccination and the rise of new variants must be addressed.

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来源
《Cell biology international.》 |2022年第12期|2009-2017|共9页
作者
Mohammad Ali Zolfaghari; Farzaneh Ghadiri Moghaddam; Shabnam RajputAbbas KarimiMohadeseh Naghi VishtehAta MahmoodpoorSanam DolatiMehdi Yousefi;
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作者单位

Student Research Committee,Tabriz University of Medical Sciences;

Department of Biology, Faculty of Science,Azarbaijan Shahid Madani University;

Department of Pediatrics, School of Medicine,Jahrom University of Medical SciencesDepartment of Molecular Medicine, Faculty of Advanced Medical Sciences,Tabriz University of MedicalDepartment of Genetics and Molecular Biology, School of Medicine,Isfahan University of MedicalDepartment of Anesthesiology,Tabriz University of Medical SciencesPhysical Medicine and Rehabilitation Research Center, Aging Research Institute,Tabriz University ofStem Cell Research Center,Tabriz University of Medical Sciences;

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原文格式 PDF
正文语种英语
中图分类细胞生物学;
关键词
antibody‐dependent enhancement; neutralizing antibodies; SARS‐CoV‐2; vaccine;

SARS‐CoV‐2 vaccines: A double‐edged sword throughout rapid evolution of COVID‐19

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