Nipah Virus: An Updated Review and Emerging Challenges

Mohamed Gabra; Hazem Ghaith; Mahmoud Ebada

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Nipah Virus: An Updated Review and Emerging Challenges

机译：Nipah Virus: An Updated Review and Emerging Challenges

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Many hospitals are teetering on the edge of being overwhelmed, with many already there because of the COVID-19 pandemic. Moreover, a recent report has also warned about the Nipah virus (NiV). NiV is a pleomorphic enveloped virus that belongs to the Paramyxoviridae family (genus Henipavirus); it affects both the respiratory and central nervous systems, with a fatality rate ranging from 40% to 75%, as documented by the World Health Organization. The first reported NiV outbreak was in early 1999 in Malaysia among people who contacted infected pigs. NiV also affected Bangladesh and India, where the main infection route was the consumption of raw date palm sap contaminated by bats. The World Health Organization has listed NiV as one of the emerging pathogens that can lead to severe outbreaks at any moment in the future with limited medical preparations and only a few projects in pharmaceutical firms. There is no licensed treatment for human use against NiV until now, and the management is limited to supportive care and symptomatic treatment. In severe cases with neurologic and respiratory complications, intensive care is needed. This article reviews the published literature and highlights the latest updates about this emerging pathogen and the methods to avoid the spread of this disease during this critical period.

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来源
《Infectious disorders drug targets》 |2022年第4期|33-40|共8页
作者
Mohamed Gabra; Hazem Ghaith; Mahmoud Ebada;
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作者单位

Faculty of Medicine, South Valley University, Qena, Egypt,Egypt,;

Faculty of Medicine, Al-Azhar University, Cairo, Egypt,Egypt,;

Faculty of Medicine, Zagazig University, Zagazig, El-Sharkia, Egypt,Egypt,|Internal Medicine;

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原文格式 PDF
正文语种英语
中图分类药学;
关键词
Nipah; epidemiology; pandemic; COV-SARS-2; COVID-19; public health.;

Nipah Virus: An Updated Review and Emerging Challenges

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