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首页> 外文期刊>Depression research and treatment >Examination and Comparison of Cognitive and Executive Functions in Clinically Stable Schizophrenia Disorder, Bipolar Disorder, and Major Depressive Disorder
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Examination and Comparison of Cognitive and Executive Functions in Clinically Stable Schizophrenia Disorder, Bipolar Disorder, and Major Depressive Disorder

机译：临床稳定型精神分裂症、双相情感障碍和重度抑郁症的认知和执行功能的检查和比较

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Background. Schizophrenia (SC), bipolar disorder (BD), and major depressive disorder (MDD) are associated with various cognitive and executive dysfunctions. The aim of the present study was to evaluate and compare cognitive and executive dysfunctions in schizophrenia, bipolar disorder, and major depressive disorder. Materials and Methods. Sixty-four schizophrenia patients, 68 bipolar patients, 62 patients with major depressive disorder, and 75 healthy individuals participated in the present study. All participants were assessed with the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I), Young Mania Rating Scale (YMRS), Positive and Negative Syndrome Scale (PANSS), Beck Depression Inventory (BDI-II), Trial Making Test (TMT), Four-Choice Reaction Time Task, Ruler Drop Method (RDM), Tower of London (TOL) task, and the Wisconsin Card Sorting Task (WCST). Data were analyzed by chi-square, Kolmogorov-Smirnov, and independent t-tests; ANOVA; and MANOVA. Results. In the cognitive function, the scores of SC, BD, and MDD patients were lower than those of healthy individuals. Also, the scores of MDD patients were lower than those of other patients, and the scores of BD patients were lower than those of SC patients. In the executive function, the scores of SC, BD, and MDD patients were lower than those of healthy individuals. Moreover, the scores of the MDD group were higher than those of the BD and SC groups, and the scores of the SC group were higher than those of the BD group. Conclusion. Patients with SC, BD, and MDD have poorer cognitive and executive functions than healthy individuals, even when these patients are in a stable state. Assessment of cognitive and executive functions in SC, BD, and MDD patients can help in understanding the pathology of these disorders.
机译：背景。精神分裂症 （SC）、双相情感障碍 （BD） 和重度抑郁症 （MDD） 与各种认知和执行功能障碍有关。本研究的目的是评估和比较精神分裂症、双相情感障碍和重度抑郁症的认知和执行功能障碍。材料和方法。64 名精神分裂症患者、68 名双相情感障碍患者、62 名重度抑郁症患者和 75 名健康人参加了本研究。所有参与者均接受 DSM-IV 轴 I 障碍结构化临床访谈 （SCID-I）、年轻躁狂评定量表 （YMRS）、阳性和阴性综合征量表 （PANSS）、贝克抑郁量表 （BDI-II）、试验测试 （TMT）、四选反应时间任务、标尺下降法 （RDM）、伦敦塔 （TOL） 任务和威斯康星卡片分类任务 （WCST） 的评估。采用χ2、Kolmogorov-Smirnov和独立t检验分析数据;方差分析;和多元方差分析。结果。在认知功能方面，SC、BD和MDD患者的得分低于健康人。此外，MDD患者的评分低于其他患者，BD患者的评分低于SC患者。在执行功能方面，SC、BD和MDD患者的评分低于健康人。MDD组得分高于BD组和SC组，SC组得分高于BD组。结论。SC、BD 和 MDD 患者的认知和执行功能比健康人差，即使这些患者处于稳定状态。评估 SC、BD 和 MDD 患者的认知和执行功能有助于了解这些疾病的病理学。

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