A Nanoporous Carbon-MXene Heterostructured Nanocomposite-Based Epidermal Patch for Real-Time Biopotentials and Sweat Glucose Monitoring

Md Abu Zahed; Md Sharifuzzaman; Hyosang YoonMd AsaduzzamanDong Kyun KimSeonghoon JeongGagan Bahadur PradhanYoung Do ShinSang Hyuk YoonSudeep SharmaShipeng Zhangand Jae Yeong Park

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A Nanoporous Carbon-MXene Heterostructured Nanocomposite-Based Epidermal Patch for Real-Time Biopotentials and Sweat Glucose Monitoring

机译：A Nanoporous Carbon-MXene Heterostructured Nanocomposite-Based Epidermal Patch for Real-Time Biopotentials and Sweat Glucose Monitoring

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摘要

Despite substantial progress in the development of wearable and flexiblemonitoring systems that conform to the epidermis, most designs focus oneither physiological signs such as the electrocardiogram (ECG) results, respirationrate, or metabolites, and ignore the dynamic fluctuations of pH andtemperature in sweat during on-body tests. An advanced butterfly-inspiredhybrid epidermal biosensing (bi-HEB) patch is presented here, which is interfacedwith a custom-developed miniaturized monitoring system. The patchincorporates a novel transducing layer of nanoporous carbon and MXene(NPC@MXene) for sensitive and durable detection of biomarkers in sweat.The bi-HEB patch is composed of a glucose biosensor accompanied by pHand temperature sensors to precisely quantify glucose as well as two biopotentialelectrodes, allowing real-time recording of electrophysiological (EP) signals.The NPC@MXene-based glucose biosensor demonstrates an excellentsensitivity of 100.85 μAmm~(?1)cm~(?2) within physiological levels (0.003?1.5 mm),and variations in pH and temperature during on-body perspiration monitoringare calibrated by employing a correction approach. In parallel, the EP electrodesexhibit skin-electrode contact impedance and biopotential signalssimilar to those of conventional Ag/AgCl electrodes. Finally, the bi-HEB patchintegrated wearable system is used to accurately monitor sweat glucose andECG of human subjects participating in indoor physical activities.

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来源
《Advanced functional materials》 |2022年第49期|2208344.1-2208344.17|共17页
作者
Md Abu Zahed; Md Sharifuzzaman; Hyosang YoonMd AsaduzzamanDong Kyun KimSeonghoon JeongGagan Bahadur PradhanYoung Do ShinSang Hyuk YoonSudeep SharmaShipeng Zhangand Jae Yeong Park;
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Advanced Sensor and Energy Research LaboratoryDepartment of Electronic EngineeringKwangwoon University447-1, Seoul 139-701, Republic of Korea;

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正文语种英语
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biopotential; glucose; MXenes; nanoporous carbons;

A Nanoporous Carbon-MXene Heterostructured Nanocomposite-Based Epidermal Patch for Real-Time Biopotentials and Sweat Glucose Monitoring

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