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首页> 外文期刊>Quality of life research: An international journal of quality of life aspects of treatment, care and rehabilitation >Is malnutrition a determining factor of health-related quality of life in hemodialysis patients? A cross-sectional design examining relationships with a comprehensive assessment of nutritional status
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Is malnutrition a determining factor of health-related quality of life in hemodialysis patients? A cross-sectional design examining relationships with a comprehensive assessment of nutritional status

机译：Is malnutrition a determining factor of health-related quality of life in hemodialysis patients? A cross-sectional design examining relationships with a comprehensive assessment of nutritional status

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Purpose To identify relationships between health-related quality of life (HRQOL) and nutritional status in hemodialysis (HD) patients. Method Secondary data from a cross-sectional survey was utilized. HRQOL was assessed for 379 HD patients using the generic Short Form 36 (SF-36) and disease-specific Kidney-Disease Quality of Life-36 (KDQOL-36). Malnutrition was indicated by malnutrition inflammation score (MIS) >= 5, and presence of protein-energy wasting (PEW). The individual nutritional parameters included the domains of physical status, serum biomarkers, and dietary intake. Multivariate associations were assessed using the general linear model. Results MIS >= 5 was negatively associated with SF-36 scores of physical functioning (MIS = 5 = 64.6 +/- 7.7 SE, P = 5 = 52.9 +/- 14.0 SE, P = 0.006), general health (MIS = 5 = 47.0 +/- 7.1 SE, P = 0.003), and PCS-36 (MIS = 5 = 35.9 +/- 3.1 SE, P = 5 = 74.8 +/- 5.4 SE, P = 0.022), but not with PEW by any tool. Of individual nutritional parameters, underweight (68.1 +/- 5.4 SE, P = 0.031), normal weight (63.8 +/- 2.8 SE, P = 0.023), and overweight (64.3 +/- 2.9 SE, P = 0.003) patients had significantly higher physical functioning scores compared to obese patients (44.8 +/- 5.5 SE). Serum albumin levels were positively associated with physical functioning (P = 0.041) score. HGS was also positively associated with physical functioning (P = 0.036), and vitality (P = 0.041) scores. Greater dietary phosphorus intakes were significantly associated with lower scores for role limitation-physical (P = 0.008), bodily pain (P = 0.043), and PCS-36 (P = 0.024). Conclusion Malnutrition diagnosis by MIS, but not PEW, indicated associations with HRQOL in HD patients. Individual nutritional parameters that related to higher HRQOL were BMI < 30 kg/m(2), better dietary phosphorus control, greater muscle strength and higher visceral protein pool.

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